Everything about Dopamine Beta Hydroxylase totally explained
| Component =
| Process =
| Orthologs =
}}
Dopamine β-hydroxylase (DBH) is an
enzyme that converts
dopamine to
norepinephrine:
Synonyms: Aromatic L-amino acid decarboxylase (
tryptophan decarboxylase, 5-hydroxytryptophan decarboxylase, AAAD) is a
lyase enzyme.
Image:Dopamin - Dopamine.svg|Dopamine
Image:Norepinephrine structure.png|Norepinephrine. Note extra hydroxyl group.
DBH is a 290 kDa copper-containing
oxygenase consisting of four identical subunits, and its activity requires
ascorbate as a
cofactor. It is the only enzyme involved in the synthesis of small-molecule neurotransmitters that's membrane-bound, making norepinephrine and epinephrine the only transmitters synthesized inside vesicles. It is expressed in noradrenergic nerve terminals of the central and peripheral nervous systems, as well as in chromaffin cells of the adrenal medulla.
DBH is inhibited by
disulfiram, tropolone, and, most selectively, by nepicastat.
Further Information
Get more info on 'Dopamine Beta Hydroxylase'.
|
External Link Exchanges
Do you know how hard it is to get a link from a large encyclopaedia? Well we're different and will prove it. To get a link from us just add the following HTML to your site on a relevant page:
<a href="http://dopamine_beta_hydroxylase.totallyexplained.com">Dopamine beta hydroxylase Totally Explained</a>
Then simply click through this link from your web page. Our crawlers will verify your link, extract the title of your web page and instantly add a link back to it. If you like you can remove the words Totally Explained and embed the link in article text.
As long as your link remains in place, we'll keep our link to you right here. Please play fair - our crawlers are watching. Your site must be closely related to this one's topic. Any kind of spamming, dubious practises or removing the link will result in your link from us being dropped and, potentially, your whole site being banned. |
